Projects

project

Ministry of Education, Spanish Agency of International Cooperation (AECI), Programme for collaboration with Brazilian universities, Grant # PHB2010- 0014, from 2013 to 2014, “Glutamina y glutaminasa como herramientas antitumorales frente al estrés metabólico y oxidativo” (“Glutamine and glutaminase as anti-cancer tools against the metabolic and oxidative stresses”). Total direct costs: 17.460 €. PI: José Manuel Matés Sánchez.

Ministry of Health and Consume, Spanish Health Institute Carlos III, RTA network from the RETICS programme, Grant # RD12/0028/0013, from 2011 to 2013, “Neurotransmisión glutamatérgica en el mecanismo de la adicción” (“Glutamatergic neurotransmission in the mechanism of drug addiction”).Total direct costs: 76.917,42 €. PI: Javier Márquez.

Regional Government of Andalucia, Excellence Research Projects 2010 Call, Grant # CVI-6656, from 2011 to 2015, “Homeostasis del glutamato en cerebro y su implicación en la adicción a cocaína y desórdenes neurológicos”(“Brain glutamate homeostasis and its involvement in neurological disorders and cocaine addiction”). Total direct costs: 165.247 €. PI: Javier Márquez.

Spanish Ministry of Science and Innovation, Grant # SAF 2010-17573, from 2011 to 2013, “Metabolismo de glutamina en el crecimiento y supervivencia celular: implicaciones para la terapia antitumoral” (“Q-metabolism in cell growth and survival: implications for anti-tumour therapy”).Total direct costs: 121.000 €. PI: Javier Márquez.

Ministry of Education, Spanish Agency of International Cooperation (AECI), Programme for collaboration with Brazilian universities, Grant # PHB2010- 0014-PC, from 2011 to 2012, “Glutamina y glutaminasa como herramientas antitumorales frente al estrés metabólico y oxidativo” (“Glutamine and glutaminase as anti-cancer tools against the metabolic and oxidative stresses”). Total direct costs: 19.275 €. PI: José Manuel Matés Sánchez.

Joint Project with the company BIONATURIS, BIOANDALUS Programme, Regional Government of Andalucia, Grant # AT2010/14/L5.3, from July, 2010 to March, 2011,“Functional characterization of recombinant human lactoferrin and its transfer to food companies as functional nutritional additive”.Total direct costs: 14.000 €. PI: Javier Márquez.

Regional Government of Andalucia, Health Department, Clinical Research Projects 2007 Call, Grant # , PI-0316/2008, from 2008 to 2010, “Correlación de la expresión tisular de las isoenzimas de glutaminasa con la agresividad de tumores humanos de alta incidencia” (“Correlation of glutaminase expression with malignancy of human tumours”). Total direct costs: 53.015,00 €. PI: Francisco J. Alonso.

Joint Project with the company BIONATURIS, BIOANDALUS Programme, Regional Government of Andalucia, Grant # 08/23/L5.4, from 2008 to 2010, “Sistema de producción de ingredientes funcionales a escala industrial” (“Production of functional nutritional ingredients at the industrial scale”). Total direct costs: 69.000 €. PI: Javier Márquez.

Ministry of Health and Consume, Spanish Health Institute Carlos III, RTA network from the RETICS programme, Grant # RD06/0001/1012, from 2008 to 2010, “Neurotransmisión glutamatérgica en el mecanismo de la adicción” (“Glutamatergic neurotransmission in the mechanism of drug addiction”). Total direct costs: 70.500 €. PI: Javier Márquez.

Spanish Ministry of Education and Science, Grant # SAF 2007-61953, from 2007 to 2010, “Análisis funcional de la Glutaminasa L en cerebro: implicación en neuroproliferación y alteraciones neurológicas” (Functional analysis of glutaminase L in brain: implication in neuroproliferation and neurological diseases”). Total direct costs: 246.840 €. PI: Javier Márquez.

Regional Government of Andalucia, Excellence Research Projects 2006 Call, Grant # CVI-01543, from 2007 to 2010, “Glutaminasa y función neuronal: análisis genómico y proteómico” (“Glutaminase and neuronal function: functional genomics and proteomics analyses”). Total direct costs: 174.536,30 €. PI: Javier Márquez.

Spanish Ministry of Education and Science, Grant # SAF2004-02339, from 2004 to 2007, “Glutaminasa como proteína multifuncional: papel en regulación transcripcional y proliferación tumoral” (“Glutaminase as a multifunctional protein: role in transcriptional regulation and tumour proliferation”). Total direct costs 172.791€. PI: Javier Márquez.

Spanish Ministry of Science and Technology, Integrated Research Projects of Genomics and Proteomics, Grant # GEN2003-20651-C06-05, from 2004 to 2007, “Análisis genómico y proteómico de la adicción a psicoestimulantes (project)” (“Genomics and Proteomics Analyses of the addiction to psychoactive drugs”). Glutamato y adicción a cocaína: evaluación funcional de las acciones de la cocaína sobre genes reguladores de la transmisión glutamatérgica (subproject).Total direct costs 110.000 €. PI: Fernando Rodríguez de Fonseca.

Regional Government of Andalucia, Grant # Acción Coordinada CVI-179, from 2001 to 2002, “Estudio diferencial de las isoformas de glutaminasa (tipos K y L) y su regulación en hemopatías malignas” (Differential study of glutaminase isoforms (K- and L-types) and their regulation in malignant hemopathies”). Total direct costs 18.030 €. PI: Javier Márquez.

Spanish Ministry of Science and Technology, Grant # CICYT SAF 2001- 1894, from 2001 to 2004, “Análisis genético y funcional de la glutaminasa humana: terapia génica basada en antisentidos de la enzima” (“Genetic and functional analysis of human glutaminase: gene therapy based on antisense targeted to the enzyme”). Total direct costs 156.263,13 €. PI: Javier Márquez.

Spanish Ministry of Science and Technology, Grant # CICYT SAF 98-0153, from 1998 to 2001, “Estructura-función de la glutaminasa tumoral: regulación de su expresión en el tumor y en tejidos del huésped” (“Structure-function of tumour glutaminase: regulation of its expression in tumour and host tissues”). Total direct costs $70.000. PI: Javier Márquez.

European Union, Training and Mobility of Researchers Programme. Research Training Grants. ERB4001GT950393, from 1996 to 1997, “Characterization of the cytokine network accompanying tumor development and its influence on nitrogen metabolism in the tumor bearing mice”. Total direct costs $47.292. PI: Javier Márquez.

Private Foundation Ramón Areces, Grant from February 1, 1995 to January 31, 1998, “Implication of glutaminase expression in the phenotype of transformed cells”. Total direct costs $70.000. PI: Ignacio Núñez de Castro.

Spanish Direccion General de Investigación Científica y Técnica, Grant # PB94 1471, August 1, 1995-August 1, 1998, “Regulation of glutaminase expression in tumour cells”. Total direct costs $70.000. PI: Javier Márquez.

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